dharmadoctors.org

from N Y Acad Sci. 2009 Aug;1172(1Longevity, Regeneration, and Optimal Health Integrating Eastern and Western Perspectives):348-361.

Bushell WC.
Anthropology Program, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
A “framework” is presented for understanding empirically confirmed and unconfirmed phenomena in the Indo-Tibetan meditation system, from an integrative perspective, and providing evidence that certain meditative practices enable meditators to realize the innate human potential to perceive light “at the limits imposed by quantum mechanics,” on the level of individual photons. This is part of a larger Buddhist agenda to meditatitively develop perceptual/attentional capacities to achieve penetrating insight into the nature of phenomena. Such capacities may also allow advanced meditators to perceive changes in natural scenes that are “hidden” from persons with “normal” attentional capacities, according to research on “change blindness,” and to enhance their visual system functioning akin to high-speed and time-lapse photography, in toto allowing for the perception, as well as sophisticated understanding, of the “moment to moment change or impermanence” universally characteristic of the phenomenal world but normally outside untrained attention and perception according to Buddhist doctrine.
PMID: 19735255

from Psychosom Med. 2009 Jan;71(1):106-14

Grant JA, Rainville P.

Département de physiologie, Université de Montréal, Montréal, Québec, Canada.

OBJECTIVE: To investigate pain perception and the potential analgesic effects of mindful states in experienced Zen meditators. METHODS: Highly trained Zen meditators (n = 13; >1000 hours of practice) and age/gender-matched control volunteers (n = 13) received individually adjusted thermal stimuli to elicit moderate pain on the calf. Conditions included: a) baseline-1: no task; b) concentration: attend exclusively to the calf; c) mindfulness: attend to the calf and observe, moment to moment, in a nonjudgmental manner; and d) baseline-2: no task. RESULTS: Meditators required significantly higher temperatures to elicit moderate pain (meditators: 49.9 degrees C; controls: 48.2 degrees C; p = .01). While attending “mindfully,” meditators reported decreases in pain intensity whereas control subjects showed no change from baseline. The concentration condition resulted in increased pain intensity for controls but not for meditators. Changes in pain unpleasantness generally paralleled those found in pain intensity. In meditators, pain modulation correlated with slowing of the respiratory rate and with greater meditation experience. Covariance analyses indicated that mindfulness-related changes could be partially explained by changes in respiratory rates. Finally, the meditators reported higher tendencies to observe and be nonreactive of their own experience as measured on the Five Factor Mindfulness Questionnaire; these factors correlated with individual differences in respiration. CONCLUSIONS: These results indicated that Zen meditators have lower pain sensitivity and experience analgesic effects during mindful states. Results may reflect cognitive/self-regulatory skills related to the concept of mindfulness and/or altered respiratory patterns. Prospective studies investigating the effects of meditative training and respiration on pain regulation are warranted.

from Harv Rev Psychiatry. 2009;17(4):254-67

Dakwar E, Levin FR.

Division of Substance Abuse, New York State Psychiatric Institute/Columbia-Presbyterian Medical Center, New York, NY 10032, USA. dakware@pi.cpmc.columbia.edu

Over the past 30 years the practice of meditation has become increasingly popular in clinical settings. In addition to evidence-based medical uses, meditation may have psychiatric benefits. In this review, the literature on the role of meditation in addressing psychiatric issues, and specifically substance use disorders, is discussed. Each of the three meditation modalities that have been most widely studied-transcendental meditation, Buddhist meditation, and mindfulness-based meditation-is critically examined in terms of its background, techniques, mechanisms of action, and evidence-based clinical applications, with special attention given to its emerging role in the treatment of substance use disorders. The unique methodological difficulties that beset the study of meditation are also considered. A brief discussion then integrates the research that has been completed thus far, elucidates the specific ways that meditation may be helpful for substance use disorders, and suggests new avenues for research.

PMID: 19637074

from Inflamm Bowel Dis. 2009 Aug 24

Cotton S, Humenay Roberts Y, Tsevat J, Britto MT, Succop P, McGrady ME, Yi MS.

Department of Family Medicine, University of Cincinnati College of Medicine.

BACKGROUND:: Mind-body complementary and alternative medicine (CAM) modalities (e.g., relaxation or meditation) for symptom management have not been well studied in adolescents with inflammatory bowel disease (IBD). The purposes of this study were to: 1) determine the prevalence of 5 types of mind-body CAM use, and consideration of use for symptom management; 2) assess characteristics associated with regular mind-body CAM use; and 3) examine whether regular and/or considered mind-body CAM use are associated with health-related quality of life (HRQOL). METHODS:: Sixty-seven adolescents with IBD ages 12-19 recruited from a children’s hospital completed a questionnaire on CAM use and the Pediatric Quality of Life Inventory. Logistic regression models were estimated for regular and considered CAM use. RESULTS:: Participants mean (SD) age was 15.5 (2.1) years; 37 (55%) were female; 53 (79%) were white; and 20 (30%) had moderate disease severity. Adolescents used prayer (62%), relaxation (40%), and imagery (21%) once/day to once/week for symptom management. In multivariate analyses, females were more likely to use relaxation (odds ratio [OR] = 4.38, 95% confidence interval [CI] = 1.25-15.29, c statistic = 0.73). Younger adolescents were more likely to regularly use (OR = 0.63, 95% CI = 0.42-0.95, c statistic = 0.72) or consider using (OR = 0.77, 95% CI = 0.59-1.00, c statistic = 0.64) meditation. Adolescents with more severe disease (OR = 4.17, 95% CI = 1.07-16.29, c statistic = 0.83) were more willing to consider using relaxation in the future. Adolescents with worse HRQOL were more willing to consider using prayer and meditation for future symptom management (P < 0.05). CONCLUSIONS:: Many adolescents with IBD either currently use or would consider using mind-body CAM for symptom management. Inflamm Bowel Dis 2009.

PMID: 19705417

from Pediatrics. 2009 Aug 24

Black DS, Milam J, Sussman S.

Institute for Health Promotion and Disease Prevention Research, University of Southern California Keck School of Medicine, Alhambra, California.

Objective: Although the efficacy of meditation interventions has been examined among adult samples, meditation treatment effects among youth are relatively unknown. We systematically reviewed empirical studies for the health-related effects of sitting-meditative practices implemented among youth aged 6 to 18 years in school, clinic, and community settings. Methods: A systematic review of electronic databases (PubMed, Ovid, Web of Science, Cochrane Reviews Database, Google Scholar) was conducted from 1982 to 2008, obtaining a sample of 16 empirical studies related to sitting-meditation interventions among youth. Results: Meditation modalities included mindfulness meditation, transcendental meditation, mindfulness-based stress reduction, and mindfulness-based cognitive therapy. Study samples primarily consisted of youth with preexisting conditions such as high-normal blood pressure, attention-deficit/hyperactivity disorder, and learning disabilities. Studies that examined physiologic outcomes were composed almost entirely of African American/black participants. Median effect sizes were slightly smaller than those obtained from adult samples and ranged from 0.16 to 0.29 for physiologic outcomes and 0.27 to 0.70 for psychosocial/behavioral outcomes. Conclusions: Sitting meditation seems to be an effective intervention in the treatment of physiologic, psychosocial, and behavioral conditions among youth. Because of current limitations, carefully constructed research is needed to advance our understanding of sitting meditation and its future use as an effective treatment modality among younger populations.

PMID: 19706568

from J Palliat Med. 2009 Aug 28

Ando M, Morita T, Akechi T, Ito S, Tanaka M, Ifuku Y, Nakayama T.

1 Faculty of Nursing, St. Mary’s College , Fukuoka, Japan .

Abstract Objective: The primary goal of the study was to assess the efficacy of mindfulness-based meditation therapy on anxiety, depression, and spiritual well-being of Japanese patients undergoing anticancer treatment. A secondary goal was to assess the relationships among anxiety, depression, spiritual well-being, growth, appreciation, pain, and symptoms. Methods: The subjects were 28 patients who were receiving anticancer treatment. The subjects participated in two sessions of mindfulness-based meditation therapy, including breathing, yoga movement and meditation. Each patient was taught the program in the first session, then exercised at home with a CD, and subsequently met the interviewer in a second session after 2 weeks. Primary physicians recruited the patients and interviews were conducted individually by nurses or psychologists with training in the program. Patients completed preintervention and postintervention questionnaires on anxiety and depression (Hospital Anxiety and Depression Scale [HADS]), spiritual well-being (Functional Assessment of Chronic Illness Therapy-Spiritual [FACIT-Sp]), and appreciation, growth, pain, and symptoms. Results: HADS scores significantly decreased from 12 +/- 5.3 to 8.6 +/- 6.3 (p = 0.004) after the intervention, and FACIT-Sp increased from 32 +/- 6.5 to 33 +/- 6.9 (p = 0.69), but the change was not significant. There were significant associations between FACIT-Sp and HADS (r = -0.78, p = 000), FACIT-Sp and growth (r = -0.35, p = 0.04), FACIT-Sp and pain (r = -0.41, p = 0.02), and growth and appreciation (r = 0.45, p = 0.009). Conclusions: Mindfulness-based meditation therapy may be effective for anxiety and depression in Japanese cancer patients, and spiritual well-being is related to anxiety and depression, growth, and pain. The negative correlation of spirituality with growth differs from the results of previous studies and the mechanism of this effect needs to be investigated further.

PMID: 19715397

from Med Hypotheses. 2006;67(3):566-71.

Jerath R, Edry JW, Barnes VA, Jerath V.

Augusta Women’s Center, 2100 Central Avenue, Suite 6 & 7, Augusta, GA 30904, USA. RJ605R@aol.com

Pranayamic breathing, defined as a manipulation of breath movement, has been shown to contribute to a physiologic response characterized by the presence of decreased oxygen consumption, decreased heart rate, and decreased blood pressure, as well as increased theta wave amplitude in EEG recordings, increased parasympathetic activity accompanied by the experience of alertness and reinvigoration. The mechanism of how pranayamic breathing interacts with the nervous system affecting metabolism and autonomic functions remains to be clearly understood. It is our hypothesis that voluntary slow deep breathing functionally resets the autonomic nervous system through stretch-induced inhibitory signals and hyperpolarization currents propagated through both neural and non-neural tissue which synchronizes neural elements in the heart, lungs, limbic system and cortex. During inspiration, stretching of lung tissue produces inhibitory signals by action of slowly adapting stretch receptors (SARs) and hyperpolarization current by action of fibroblasts. Both inhibitory impulses and hyperpolarization current are known to synchronize neural elements leading to the modulation of the nervous system and decreased metabolic activity indicative of the parasympathetic state. In this paper we propose pranayama’s physiologic mechanism through a cellular and systems level perspective, involving both neural and non-neural elements. This theoretical description describes a common physiological mechanism underlying pranayama and elucidate the role of the respiratory and cardiovascular system on modulating the autonomic nervous system. Along with facilitating the design of clinical breathing techniques for the treatment of autonomic nervous system and other disorders, this model will also validate pranayama as a topic requiring more research.

PMID: 16624497

from  BMC Complement Altern Med. 2007 Jan 25;7:2

Davis JM, Fleming MF, Bonus KA, Baker TB.

Center for Tobacco Research and Intervention, University of Wisconsin School of Medicine and Public Health, Madison, WI 53711-2027, USA. jd4@medicine.wisc.edu

BACKGROUND: Mindfulness means paying attention in the present moment, non-judgmentally, without commentary or decision-making. We report results of a pilot study designed to test the feasibility of using Mindfulness Based Stress Reduction (MBSR) (with minor modifications) as a smoking intervention. METHODS: MBSR instructors provided instructions in mindfulness in eight weekly group sessions. Subjects attempted smoking cessation during week seven without pharmacotherapy. Smoking abstinence was tested six weeks after the smoking quit day with carbon monoxide breath test and 7-day smoking calendars. Questionnaires were administered to evaluate changes in stress and affective distress. RESULTS: 18 subjects enrolled in the intervention with an average smoking history of 19.9 cigarettes per day for 26.4 years. At the 6-week post-quit visit, 10 of 18 subjects (56%) achieved biologically confirmed 7-day point-prevalent smoking abstinence. Compliance with meditation was positively associated with smoking abstinence and decreases in stress and affective distress. DISCUSSIONS AND CONCLUSION: The results of this study suggest that mindfulness training may show promise for smoking cessation and warrants additional study in a larger comparative trial.

from  Disabil Rehabil. 2003 Jul 8;25(13):722-31

Bédard M, Felteau M, Mazmanian D, Fedyk K, Klein R, Richardson J, Parkinson W, Minthorn-Biggs MB.

Department of Psychology, Lakehead University, Lakehead Psychiatric Hospital, 955 Oliver Road, Thunder Bay, Ontario P7B 5E1, Canada. michel.bedard@lakeheadu.ca

PRIMARY OBJECTIVE: To examine the potential efficacy of a mindfulness-based stress reduction approach to improve quality of life in individuals who have suffered traumatic brain injuries. RESEARCH DESIGN: Pre-post design with drop-outs as controls. METHODS AND PROCEDURES: We recruited individuals with mild to moderate brain injuries, at least 1 year post-injury. We measured their quality of life, psychological status, and function. Results of 10 participants who completed the programme were compared to three drop-outs with complete data. EXPERIMENTAL INTERVENTION: The intervention was delivered in 12-weekly group sessions. The intervention relied on insight meditation, breathing exercises, guided visualization, and group discussion. We aimed to encourage a new way of thinking about disability and life to bring a sense of acceptance, allowing participants to move beyond limiting beliefs. MAIN OUTCOMES AND RESULTS: The treatment group mean quality of life (SF-36) improved by 15.40 (SD = 9.08) compared to - 1.67 (SD = 16.65; p = 0.036) for controls. Improvements on the cognitive-affective domain of the Beck Depression Inventory II (BDI-II) were reported (p = 0.029), while changes in the overall BDI-II (p = 0.059) and the Positive Symptom Distress Inventory of the SCL-90R (p = 0.054) approached statistical significance. CONCLUSIONS: The intervention was simple, and improved quality of life after other treatment avenues for these participants were exhausted.

PMID: 12791557

from Neuroreport. 2005 Nov 28;16(17):1893-7

Lazar SW, Kerr CE, Wasserman RH, Gray JR, Greve DN, Treadway MT, McGarvey M, Quinn BT, Dusek JA, Benson H, Rauch SL, Moore CI, Fischl B.

Psychiatric Neuroimaging Research Program, Massachusetts General Hospital, Boston, Massachusetts, USA. lazar@nmr.mgh.harvard.edu

Previous research indicates that long-term meditation practice is associated with altered resting electroencephalogram patterns, suggestive of long lasting changes in brain activity. We hypothesized that meditation practice might also be associated with changes in the brain’s physical structure. Magnetic resonance imaging was used to assess cortical thickness in 20 participants with extensive Insight meditation experience, which involves focused attention to internal experiences. Brain regions associated with attention, interoception and sensory processing were thicker in meditation participants than matched controls, including the prefrontal cortex and right anterior insula. Between-group differences in prefrontal cortical thickness were most pronounced in older participants, suggesting that meditation might offset age-related cortical thinning. Finally, the thickness of two regions correlated with meditation experience. These data provide the first structural evidence for experience-dependent cortical plasticity associated with meditation practice.